Disruption of the Circadian Clock Alters Antioxidative Defense via the SIRT1-BMAL1 Pathway in 6-OHDA-Induced Models of Parkinson's Disease

Parkinson's disease (PD) is the second most common neurodegenerative disease and is known to involve circadian dysfunction and oxidative stress. Although antioxidative defense is regulated by the molecular circadian clock, few studies have examined their function in PD and their regulation by s...

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Vydáno v:Oxid Med Cell Longev
Hlavní autoři: Wang, Yali, Lv, Dongjun, Liu, Wenwen, Li, Siyue, Chen, Jing, Shen, Yun, Wang, Fen, Hu, Li-Fang, Liu, Chun-Feng
Médium: Artigo
Jazyk:Inglês
Vydáno: Hindawi 2018
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Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5932489/
https://ncbi.nlm.nih.gov/pubmed/29849897
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2018/4854732
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