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Disruption of the Circadian Clock Alters Antioxidative Defense via the SIRT1-BMAL1 Pathway in 6-OHDA-Induced Models of Parkinson's Disease

Parkinson's disease (PD) is the second most common neurodegenerative disease and is known to involve circadian dysfunction and oxidative stress. Although antioxidative defense is regulated by the molecular circadian clock, few studies have examined their function in PD and their regulation by s...

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Detalhes bibliográficos
Publicado no:Oxid Med Cell Longev
Main Authors: Wang, Yali, Lv, Dongjun, Liu, Wenwen, Li, Siyue, Chen, Jing, Shen, Yun, Wang, Fen, Hu, Li-Fang, Liu, Chun-Feng
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5932489/
https://ncbi.nlm.nih.gov/pubmed/29849897
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2018/4854732
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