Circadian clock function is disrupted by environmental tobacco/cigarette smoke, leading to lung inflammation and injury via a SIRT1-BMAL1 pathway

Patients with obstructive lung diseases display abnormal circadian rhythms in lung function. We determined the mechanism whereby environmental tobacco/cigarette smoke (CS) modulates expression of the core clock gene BMAL1, through Sirtuin1 (SIRT1) deacetylase during lung inflammatory and injurious r...

Full description

Saved in:
Bibliographic Details
Main Authors: Hwang, Jae-Woong, Sundar, Isaac K., Yao, Hongwei, Sellix, Michael T., Rahman, Irfan
Format: Artigo
Language:Inglês
Published: Federation of American Societies for Experimental Biology 2014
Subjects:
Research Communications
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3868829/
https://ncbi.nlm.nih.gov/pubmed/24025728
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.13-232629
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items