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Cigarette smoke-induced autophagy is regulated by SIRT1-PARP-1-dependent mechanism: Implication in pathogenesis of COPD

Autophagy is a fundamental cellular process that eliminates long-lived proteins and damaged organelles through lysosomal degradation pathway. Cigarette smoke (CS)-mediated oxidative stress induces cytotoxic responses in lung cells. However, the role of autophagy and its mechanism in CS-mediated cyto...

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Autores principales: Hwang, Jae-woong, Chung, Sangwoon, Sundar, Isaac K., Yao, Hongwei, Arunachalam, Gnanapragasam, McBurney, Michael W., Rahman, Irfan
Formato: Artigo
Lenguaje:Inglês
Publicado: 2010
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2904411/
https://ncbi.nlm.nih.gov/pubmed/20493163
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.abb.2010.05.013
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