EGF Receptor and mTORC1 are novel therapeutic targets in nonseminomatous germ cell tumors

Germ cell tumors (GCTs) are malignant tumors that arise from pluripotent embryonic germ cells and occur in children and young adults. GCTs are treated with cisplatin-based regimens which, while overall effective, fail to cure all patients and cause significant adverse late effects. The seminoma and...

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Vydáno v:Mol Cancer Ther
Hlavní autoři: Chen, Kenneth S., Fustino, Nicholas J., Shukla, Abhay A., Stroup, Emily K., Budhipramono, Albert, Ateek, Christina, Stuart, Sarai H., Yamaguchi, Kiyoshi, Kapur, Payal, Frazier, A. Lindsay, Lum, Lawrence, Looijenga, Leendert H.J., Laetsch, Theodore W., Rakheja, Dinesh, Amatruda, James F.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2018
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5932259/
https://ncbi.nlm.nih.gov/pubmed/29483210
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1535-7163.MCT-17-0137
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