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Deletion of endoplasmic reticulum stress-responsive co-chaperone p58(IPK) protects mice from diet-induced steatohepatitis

Activation of the endoplasmic reticulum stress sensor PERK is a feature of nonalcoholic steatohepatitis (NASH), yet regulators of PERK signaling remain undefined in this context. P58(IPK) regulates PERK; however, its role in NASH has not been examined. Aim: the aim of this study was to assess the in...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Hepatol Res
Hauptverfasser: Bandla, Harikrishna, Dasgupta, Debanjali, Mauer, Amy S., Nozickova, Barbora, Kumar, Swarup, Hirsova, Petra, Graham, Rondell P., Malhi, Harmeet
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2018
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5932231/
https://ncbi.nlm.nih.gov/pubmed/29316085
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/hepr.13052
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