Broad and diverse mechanisms used by deubiquitinase family members in regulating the type I interferon signaling pathway during antiviral responses

The innate immune response conferred by type I interferons is essential for host defense against viral infection but needs to be tightly controlled to avoid immunopathology. We performed a systematic functional screening by CRISPR/Cas9 (clustered regularly interspaced short palindromic repeats/CRISP...

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Detalhes bibliográficos
Publicado no:Sci Adv
Principais autores: Liu, Qingxiang, Wu, Yaoxing, Qin, Yunfei, Hu, Jiajia, Xie, Weihong, Qin, F. Xiao-Feng, Cui, Jun
Formato: Artigo
Idioma:Inglês
Publicado em: American Association for the Advancement of Science 2018
Assuntos:
Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5931765/
https://ncbi.nlm.nih.gov/pubmed/29732405
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/sciadv.aar2824
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