NLRP11 disrupts MAVS signalosome to inhibit type I interferon signaling and virus‐induced apoptosis

MAVS signalosome plays an important role in RIG‐I‐like receptor (RLR)‐induced antiviral signaling. Upon the recognition of viral RNAs, RLRs activate MAVS, which further recruits TRAF6 and other signaling proteins to initiate type I interferon (IFN) activation. MAVS signalosome also regulates virus‐i...

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Detalhes bibliográficos
Publicado no:EMBO Rep
Main Authors: Qin, Yunfei, Su, Zexiong, Wu, Yaoxing, Wu, Chenglei, Jin, Shouheng, Xie, Weihong, Jiang, Wei, Zhou, Rongbin, Cui, Jun
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2017
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5709773/
https://ncbi.nlm.nih.gov/pubmed/29097393
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embr.201744480
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