NLRP11 disrupts MAVS signalosome to inhibit type I interferon signaling and virus‐induced apoptosis

MAVS signalosome plays an important role in RIG‐I‐like receptor (RLR)‐induced antiviral signaling. Upon the recognition of viral RNAs, RLRs activate MAVS, which further recruits TRAF6 and other signaling proteins to initiate type I interferon (IFN) activation. MAVS signalosome also regulates virus‐i...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:EMBO Rep
Hauptverfasser: Qin, Yunfei, Su, Zexiong, Wu, Yaoxing, Wu, Chenglei, Jin, Shouheng, Xie, Weihong, Jiang, Wei, Zhou, Rongbin, Cui, Jun
Format: Artigo
Sprache:Inglês
Veröffentlicht: John Wiley and Sons Inc. 2017
Schlagworte:
Articles
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5709773/
https://ncbi.nlm.nih.gov/pubmed/29097393
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embr.201744480
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!

Ähnliche Einträge