Zika virus antagonizes interferon response in patients and disrupts RIG-I–MAVS interaction through its CARD-TM domains

BACKGROUND: The emerging threat to global health associated with the Zika virus (ZIKV) epidemics and its link to severe complications highlights a growing need to better understand the pathogenic mechanisms of ZIKV. Accumulating evidence for a critical role of type I interferon (IFN-I) in protecting...

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Gepubliceerd in:Cell Biosci
Hoofdauteurs: Hu, Yiwen, Dong, Xinhuai, He, Zhenjian, Wu, Yun, Zhang, Shihao, Lin, Jiajie, Yang, Yi, Chen, Jiahui, An, Shu, Yin, Yingxian, Shen, Zhiyong, Zeng, Gucheng, Tian, Han, Cai, Junchao, Guan, Hongyu, Wu, Jueheng, Li, Mengfeng, Zhu, Xun
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: BioMed Central 2019
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Research
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6555941/
https://ncbi.nlm.nih.gov/pubmed/31183075
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13578-019-0308-9
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