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Plk1 phosphorylation of Numb leads to impaired DNA damage response
Although Numb is well-recognized as a cell-fate determinant in stem/progenitor cells, accumulating evidence supports that Numb also has a critical role in adult tissues and cancers, in particular, in the context of regulation of tumor suppressor p53. Herein, we identified Numb as a novel substrate o...
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| Publicado en: | Oncogene |
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| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
2017
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5931337/ https://ncbi.nlm.nih.gov/pubmed/29059161 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/onc.2017.379 |
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