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Engineered T cells targeting E7 mediate regression of human papillomavirus cancers in a murine model
T cell receptor (TCR) T cell therapy is a promising cancer treatment modality. However, its successful development for epithelial cancers may depend on the identification of high-avidity TCRs directed against tumor-restricted target antigens. The human papillomavirus (HPV) E7 antigen is an attractiv...
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| Pubblicato in: | JCI Insight |
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| Autori principali: | , , , , , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
American Society for Clinical Investigation
2018
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5931134/ https://ncbi.nlm.nih.gov/pubmed/29669936 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.99488 |
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