Macrophages induce “budding” in aggressive human colon cancer subtypes by protease-mediated disruption of tight junctions

Primary human colorectal tumors with a high stromal content have an increased capacity to metastasize. Cancer-associated fibroblasts (CAFs) promote metastasis, but the contribution of other stromal cell types is unclear. Here we searched for additional stromal cell types that contribute to aggressiv...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Trumpi, Kari, Frenkel, Nicola, Peters, Timo, Korthagen, Nicoline M., Jongen, Jennifer M.J., Raats, Daniëlle, van Grevenstein, Helma, Backes, Yara, Moons, Leon M., Lacle, Miangela M., Koster, Jan, Zwijnenburg, Danny, Borel Rinkes, Inne H.M., Kranenburg, Onno
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2018
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5929404/
https://ncbi.nlm.nih.gov/pubmed/29731961
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.24626
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