ALDH1A1 expression is associated with poor differentiation, ‘right-sidedness’ and poor survival in human colorectal cancer

BACKGROUND: Aldehyde dehydrogenase 1A1 (ALDH1A1) encodes an enzyme that oxidizes aldehydes to their corresponding carboxylic acids. In colorectal cancer ALDH1A1 marks cancer stem cells and plays putative roles in tumor progression and drug resistance. However, the potential value of ALDH1A1 as a dia...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: van der Waals, Lizet M., Borel Rinkes, Inne H. M., Kranenburg, Onno
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2018
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6181398/
https://ncbi.nlm.nih.gov/pubmed/30308036
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0205536
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