Paired image- and FACS-based toxicity assays for high content screening of spheroid-type tumor cell cultures

Novel spheroid-type tumor cell cultures directly isolated from patients’ tumors preserve tumor characteristics better than traditionally grown cell lines. However, such cultures are not generally used for high-throughput toxicity drug screens. In addition, the assays that are commonly used to assess...

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發表在:FEBS Open Bio
Main Authors: Trumpi, Kari, Egan, David A., Vellinga, Thomas T., Borel Rinkes, Inne H.M., Kranenburg, Onno
格式: Artigo
語言:Inglês
出版: Elsevier 2015
主題:
Method
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC4325131/
https://ncbi.nlm.nih.gov/pubmed/25685667
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.fob.2015.01.003
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