In Vivo PET Assay of Tumor Glutamine Flux and Metabolism: In-Human Trial of (18)F-(2S,4R)-4-Fluoroglutamine

PURPOSE: To assess the clinical safety, pharmacokinetics, and tumor imaging characteristics of fluorine 18–(2S,4R)-4-fluoroglutamine (FGln), a glutamine analog radiologic imaging agent. MATERIALS AND METHODS: This study was approved by the institutional review board and conducted under a U.S. Food a...

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Detaylı Bibliyografya
Yayımlandı:Radiology
Asıl Yazarlar: Dunphy, Mark P. S., Harding, James J., Venneti, Sriram, Zhang, Hanwen, Burnazi, Eva M., Bromberg, Jacqueline, Omuro, Antonio M., Hsieh, James J., Mellinghoff, Ingo K., Staton, Kevin, Pressl, Christina, Beattie, Bradley J., Zanzonico, Pat B., Gerecitano, John F., Kelsen, David P., Weber, Wolfgang, Lyashchenko, Serge K., Kung, Hank F., Lewis, Jason S.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Radiological Society of North America 2018
Konular:
Original Research
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC5929369/
https://ncbi.nlm.nih.gov/pubmed/29388903
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1148/radiol.2017162610
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