TM-15 GLUTAMINE BASED PET IMAGING FACILITATES ENHANCED METABOLIC DETECTION OF GLIOMAS IN VIVO

Glutamine is the most abundant plasma amino acid and many cancers show altered glutamine metabolism. We evaluated glutamine uptake and metabolism in gliomas using PET imaging and biochemical approaches. We demonstrate that glutamine is a key TCA cycle anaplerotic substrate and is metabolized to gene...

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Bibliografiska uppgifter
I publikationen:Neuro Oncol
Huvudupphovsmän: Venneti, Sriram, Dunphy, Mark, Zhang, Hanwen, Pitter, Kenneth, Campos, Carl, Carlin, Sean, Lyashchenko, Serge, Plöessl, Carl, Rohle, Daniel, Omuro, Antonio, Cross, Justin, Brennan, Cameron, Weber, Wolfgang, Holland, Eric, Mellinghoff, Ingo, Kung, Hank, Lewis, Jason, Thompson, Craig
Materialtyp: Artigo
Språk:Inglês
Publicerad: Oxford University Press 2014
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Abstracts
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4218624/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/nou278.14
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