In Vivo PET Assay of Tumor Glutamine Flux and Metabolism: In-Human Trial of (18)F-(2S,4R)-4-Fluoroglutamine

PURPOSE: To assess the clinical safety, pharmacokinetics, and tumor imaging characteristics of fluorine 18–(2S,4R)-4-fluoroglutamine (FGln), a glutamine analog radiologic imaging agent. MATERIALS AND METHODS: This study was approved by the institutional review board and conducted under a U.S. Food a...

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Detalhes bibliográficos
Publicado no:Radiology
Main Authors: Dunphy, Mark P. S., Harding, James J., Venneti, Sriram, Zhang, Hanwen, Burnazi, Eva M., Bromberg, Jacqueline, Omuro, Antonio M., Hsieh, James J., Mellinghoff, Ingo K., Staton, Kevin, Pressl, Christina, Beattie, Bradley J., Zanzonico, Pat B., Gerecitano, John F., Kelsen, David P., Weber, Wolfgang, Lyashchenko, Serge K., Kung, Hank F., Lewis, Jason S.
Formato: Artigo
Idioma:Inglês
Publicado em: Radiological Society of North America 2018
Assuntos:
Original Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5929369/
https://ncbi.nlm.nih.gov/pubmed/29388903
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1148/radiol.2017162610
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