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Unrestrained p38 MAPK Activation in Dusp1/4 Double Null Mice Induces Cardiomyopathy
RATIONALE: Mitogen-activated protein kinases (MAPKs) are activated in the heart by disease- and stress-inducing stimuli where they participate in hypertrophy, remodeling, contractility, and heart failure. A family of dual-specificity phosphatases (DUSPs) directly inactivates each of the MAPK termina...
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| Publicado no: | Circ Res |
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| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5929162/ https://ncbi.nlm.nih.gov/pubmed/22993413 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCRESAHA.112.272963 |
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