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DUSP8 Regulates Cardiac Ventricular Remodeling by Altering ERK1/2 Signaling

RATIONALE: Mitogen-activated protein kinase (MAPK) signaling regulates the growth response of the adult myocardium in response to increased cardiac workload or pathologic insults. The dual-specificity phosphatases (DUSPs) are critical effectors that dephosphorylate the MAPKs to control the basal ton...

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Detalles Bibliográficos
Publicado en:Circ Res
Main Authors: Liu, Ruijie, van Berlo, Jop H., York, Allen J., Maillet, Marjorie, Vagnozzi, Ronald J., Molkentin, Jeffery D.
Formato: Artigo
Idioma:Inglês
Publicado: 2016
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4938738/
https://ncbi.nlm.nih.gov/pubmed/27225478
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCRESAHA.115.308238
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