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Transcriptional Dysregulation of MYC Reveals Common Enhancer-Docking Mechanism
Transcriptional dysregulation of the MYC oncogene is among the most frequent events in aggressive tumor cells, and this is generally accomplished by acquisition of a super-enhancer somewhere within the 2.8 Mb TAD where MYC resides. We find that these diverse cancer-specific super-enhancers, differin...
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| 發表在: | Cell Rep |
|---|---|
| Main Authors: | , , , , , , , |
| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
2018
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5929158/ https://ncbi.nlm.nih.gov/pubmed/29641996 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2018.03.056 |
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