A functional genomic screen in vivo identifies CEACAM5 as a clinically relevant driver of breast cancer metastasis

Tumor cells disseminate early in tumor development making metastasis-prevention strategies difficult. Identifying proteins that promote the outgrowth of disseminated tumor cells may provide opportunities for novel therapeutic strategies. Despite multiple studies demonstrating that the mesenchymal-to...

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Publicado no:NPJ Breast Cancer
Main Authors: Powell, Emily, Shao, Jiansu, Picon, Hector M., Bristow, Christopher, Ge, Zhongqi, Peoples, Michael, Robinson, Frederick, Jeter-Jones, Sabrina L., Schlosberg, Christopher, Grzeskowiak, Caitlin L., Yang, Fei, Wu, Yun, Wistuba, Ignacio, Moulder, Stacy L., Symmans, William F., Scott, Kenneth L., Edwards, John R., Liang, Han, Heffernan, Timothy P., Piwnica-Worms, Helen
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2018
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5928229/
https://ncbi.nlm.nih.gov/pubmed/29736411
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41523-018-0062-x
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