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Immobilized fibrinogen activates human platelets through glycoprotein VI
Glycoprotein VI, a major platelet activation receptor for collagen and fibrin, is considered a particularly promising, safe antithrombotic target. In this study, we show that human glycoprotein VI signals upon platelet adhesion to fibrinogen. Full spreading of human platelets on fibrinogen was aboli...
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| Veröffentlicht in: | Haematologica |
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| Hauptverfasser: | , , , , , , , , , , , , , , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Ferrata Storti Foundation
2018
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5927996/ https://ncbi.nlm.nih.gov/pubmed/29472360 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3324/haematol.2017.182972 |
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