HIF1-alpha Regulates Acinar Cell Function and Response to Injury in Mouse Pancreas

We investigated whether intra-pancreatic coagulation, with deposition of the fibrinogen-γ dimer (Fib-γD) and hypoxia, affect the severity of acute pancreatitis (AP) in mice. Pancreata of mice with AP induced by administration of cerulein or by L-arginine, or from patients with AP, had increased depo...

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Publicado en:Gastroenterology
Autores principales: Park, Min-Jung, Iyer, Sapna, Xue, Xiang, Cunha, Juliana Bragazzi, Gu, Shufang, Moons, David, Pipe, Steven W., Williams, John A., Simeone, Diane M., Shah, Yatrik M., Omary, M. Bishr
Formato: Artigo
Lenguaje:Inglês
Publicado: 2018
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5927829/
https://ncbi.nlm.nih.gov/pubmed/29409830
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1053/j.gastro.2018.01.037
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