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The Hypoxia-Inducible Factor–C/EBPα Axis Controls Ethanol-Mediated Hepcidin Repression

Hepcidin is a liver-derived peptide hormone and the master regulator of systemic iron homeostasis. Decreased hepcidin expression is a common feature in alcoholic liver disease (ALD) and in mouse models of ethanol loading. Dysregulation of hepcidin signaling in ALD leads to liver iron deposition, whi...

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Bibliografische gegevens
Hoofdauteurs: Anderson, Erik R., Taylor, Matthew, Xue, Xiang, Martin, Angelical, Moons, David S., Omary, M. Bishr, Shah, Yatrik M.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: American Society for Microbiology 2012
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3457545/
https://ncbi.nlm.nih.gov/pubmed/22869521
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00723-12
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