Hypoxia-Inducible Factor-2α Mediates the Adaptive Increase of Intestinal Ferroportin During Iron Deficiency in Mice

BACKGROUND & AIMS: Iron deficiency and iron overload affect over a billion people, worldwide. Dietary iron absorption in the small intestine is required for systemic iron homeostasis. Ferroportin (FPN) is the only characterized, mammalian, basolateral iron exporter. Despite the importance of FPN...

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Bibliographic Details
Main Authors: Taylor, Matthew, Qu, Aijuan, Anderson, Erik R, Matsubara, Tsutomu, Martin, Angelical, Gonzalez, Frank J., Shah, Yatrik M.
Format: Artigo
Language:Inglês
Published: 2011
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3109109/
https://ncbi.nlm.nih.gov/pubmed/21419768
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1053/j.gastro.2011.03.007
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