Lack of a Dose‐response Relationship for Carcinogenicity in the Rat Liver with Low Doses of 2‐Amino‐3,8‐dimethylimidazo[4,5‐f]quinoxaline or N‐Nitrosodiethylamine

For a long period, it has been generally considered that carcinogens, particularly genotoxic ones, have no threshold in exerting their potential for cancer induction. However, the non‐threshold theory can be challenged with regard to assessment of cancer risk to humans. Here we show that a food‐deri...

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Veröffentlicht in:Jpn J Cancer Res
Hauptverfasser: Fukushima, Shoji, Wanibuchi, Hideki, Morimura, Keiichirou, Wei, Min, Nakae, Dai, Konishi, Yoichi, Tsuda, Hiroyuki, Uehara, Nobuaki, Imaida, Katsumi, Shirai, Tomoyuki, Tatematsu, Masae, Tsukamoto, Tetsuya, Hirose, Masao, Furukawa, Fumio, Wakabayashi, Keiji, Totsuka, Yukari
Format: Artigo
Sprache:Inglês
Veröffentlicht: Blackwell Publishing Ltd 2002
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5926877/
https://ncbi.nlm.nih.gov/pubmed/12417036
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1349-7006.2002.tb01208.x
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