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DNA Adducts Formed by 2‐Amino‐3,8‐dimethylimidazo[4,5‐f]quinoxaline in Rat Liver: Dose‐Response on Chronic Administration

The effect of administration of 2‐amino‐3,8‐dimethylimidazo[4,5‐f]quinoxaline (MeIQx) at various doses on DNA adduct formation in male rats was examined by (32)P‐postlabeling analysis. Administration of MeIQx in the diet at 0.4 ppm, 4 ppm, 40 ppm and 400 ppm for one week resulted in the formations o...

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Detalhes bibliográficos
Publicado no:Jpn J Cancer Res
Main Authors: Yamashita, Katsumi, Adachi, Masaaki, Kato, Shunji, Nakagama, Hitoshi, Ochiai, Masako, Wakabayashi, Keiji, Sato, Shigeaki, Nagao, Minako, Sugimura, Takashi
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Publishing Ltd 1990
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5918071/
https://ncbi.nlm.nih.gov/pubmed/2116395
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1349-7006.1990.tb02593.x
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