Lack of Carcinogenicity of 2‐Amino‐3,8‐dimethylimidazo[4,5‐f]quinoxaline (MeIQx) in Cynomolgus Monkeys

The carcinogenic potential of 2‐amino‐3,8‐dimethylimidazo[4,5‐f]quinoxaline (MeIQx) was evaluated in cynomolgus monkeys. The animals received MeIQx, beginning at the age of one year, at doses of 10 or 20 mg/kg body weight by gavage five times a week for 84 months and were autopsied 8 months thereaft...

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Publicado en:Jpn J Cancer Res
Main Authors: Ogawa, Kumiko, Tsuda, Hiroyuki, Shirai, Tomoyuki, Ogiso, Tadashi, Wakabayashi, Keiji, Dalgard, Dan W., Thorgeirsson, Unnur P., Thorgeirsson, Snorri S., Adamson, Richard H., Sugimura, Takashi
Formato: Artigo
Idioma:Inglês
Publicado: Blackwell Publishing Ltd 1999
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5926120/
https://ncbi.nlm.nih.gov/pubmed/10429653
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1349-7006.1999.tb00792.x
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