High Expression of Thymidylate Synthase Leads to Resistance to 5‐Fluorouracil in Biliary Tract Carcinoma in vitro

To evaluate the effect of chemotherapy of 5‐fluorouracil (5‐FU) in human biliary tract carcinoma, we studied 5‐FU sensitivity, thymidylate synthase (TS) content, and dihydropyrimidine dehydroge‐nase (DPD) activity in 4 human biliary tract carcinoma cell lines compared to 12 various digestive carcino...

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Vydáno v:Jpn J Cancer Res
Hlavní autoři: Habara, Kazuto, Ajiki, Tetsuo, Kamigaki, Takashi, Nakamura, Takeshi, Kuroda, Yoshikazu
Médium: Artigo
Jazyk:Inglês
Vydáno: Blackwell Publishing Ltd 2001
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5926613/
https://ncbi.nlm.nih.gov/pubmed/11676864
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1349-7006.2001.tb01068.x
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