Protection against Malignant Progression of Spontaneously Developing Liver Tumors in Transgenic Mice Expressing O(6)‐Methylguanine‐DNA Methyltransferase

To study the effect of O(6)‐methylguanine‐DNA methyltransferase (MGMT) on carcinogenesis, we have previously generated MGMT transgenic mice overexpressing the bacterial MGMT gene, ada, and demonstrated that high MGMT levels in the liver suppress induction of liver tumors after treatment with an alky...

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Detalhes bibliográficos
Publicado no:Jpn J Cancer Res
Main Authors: Qin, Xiusheng, Zhang, Shaomin, Matsukuma, Shoichi, Zarkovic, Mirjana, Shimizu, Seiichiro, Ishikawa, Takatoshi, Nakatsuru, Yoko
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Publishing Ltd 2000
Assuntos:
Rapid Communication
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5926285/
https://ncbi.nlm.nih.gov/pubmed/11092970
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1349-7006.2000.tb00888.x
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