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Protection against Malignant Progression of Spontaneously Developing Liver Tumors in Transgenic Mice Expressing O(6)‐Methylguanine‐DNA Methyltransferase

To study the effect of O(6)‐methylguanine‐DNA methyltransferase (MGMT) on carcinogenesis, we have previously generated MGMT transgenic mice overexpressing the bacterial MGMT gene, ada, and demonstrated that high MGMT levels in the liver suppress induction of liver tumors after treatment with an alky...

詳細記述

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書誌詳細
出版年:Jpn J Cancer Res
主要な著者: Qin, Xiusheng, Zhang, Shaomin, Matsukuma, Shoichi, Zarkovic, Mirjana, Shimizu, Seiichiro, Ishikawa, Takatoshi, Nakatsuru, Yoko
フォーマット: Artigo
言語:Inglês
出版事項: Blackwell Publishing Ltd 2000
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC5926285/
https://ncbi.nlm.nih.gov/pubmed/11092970
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1349-7006.2000.tb00888.x
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