Protection against Malignant Progression of Spontaneously Developing Liver Tumors in Transgenic Mice Expressing O(6)‐Methylguanine‐DNA Methyltransferase

To study the effect of O(6)‐methylguanine‐DNA methyltransferase (MGMT) on carcinogenesis, we have previously generated MGMT transgenic mice overexpressing the bacterial MGMT gene, ada, and demonstrated that high MGMT levels in the liver suppress induction of liver tumors after treatment with an alky...

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Publicat a:Jpn J Cancer Res
Autors principals: Qin, Xiusheng, Zhang, Shaomin, Matsukuma, Shoichi, Zarkovic, Mirjana, Shimizu, Seiichiro, Ishikawa, Takatoshi, Nakatsuru, Yoko
Format: Artigo
Idioma:Inglês
Publicat: Blackwell Publishing Ltd 2000
Matèries:
Rapid Communication
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5926285/
https://ncbi.nlm.nih.gov/pubmed/11092970
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1349-7006.2000.tb00888.x
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