O6-methylguanine-DNA methyltransferase protects against nitrosamine-induced hepatocarcinogenesis.

We previously generated transgenic C3H/HeN mice by introducing the Escherichia coli O6-methylguanine-DNA methyltransferase (MGMT, DNA-O6-methylguanine:protein-L-cysteine S-methyltransferase, EC2.1.1.63) gene, ada, attached to the Chinese hamster metallothionein I gene promoter. One transgenic mouse...

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Pubblicato in:	Proc Natl Acad Sci U S A
Autori principali:	Nakatsuru, Y, Matsukuma, S, Nemoto, N, Sugano, H, Sekiguchi, M, Ishikawa, T
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	National Academy of Sciences 1993
Soggetti:	Research Article
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC46953/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8341657/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.90.14.6468
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