O6-methylguanine-DNA methyltransferase protects against nitrosamine-induced hepatocarcinogenesis.
We previously generated transgenic C3H/HeN mice by introducing the Escherichia coli O6-methylguanine-DNA methyltransferase (MGMT, DNA-O6-methylguanine:protein-L-cysteine S-methyltransferase, EC2.1.1.63) gene, ada, attached to the Chinese hamster metallothionein I gene promoter. One transgenic mouse...
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| Vydáno v: | Proc Natl Acad Sci U S A |
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| Hlavní autoři: | , , , , , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
National Academy of Sciences
1993
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC46953/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8341657/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.90.14.6468 |
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