O6-methylguanine-DNA methyltransferase protects against nitrosamine-induced hepatocarcinogenesis.

We previously generated transgenic C3H/HeN mice by introducing the Escherichia coli O6-methylguanine-DNA methyltransferase (MGMT, DNA-O6-methylguanine:protein-L-cysteine S-methyltransferase, EC2.1.1.63) gene, ada, attached to the Chinese hamster metallothionein I gene promoter. One transgenic mouse...

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Enregistré dans:
Détails bibliographiques
Auteurs principaux: Nakatsuru, Y, Matsukuma, S, Nemoto, N, Sugano, H, Sekiguchi, M, Ishikawa, T
Format: Artigo
Langue:Inglês
Publié: 1993
Sujets:
Research Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC46953/
https://ncbi.nlm.nih.gov/pubmed/8341657
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