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Methylenetetrahydrofolate Reductase Genotype in Diffuse Large B-Cell Lymphomas with and without Hypermethylation of the DNA Repair Gene O-Methylguanine DNA Methyltransferase

C677T and A1298C methylenetetrahydrofolate reductase (MTHFR) polymorphisms have been suggested to affect susceptibility to malignant lymphoma, possibly by altering DNA methylation. The DNA repair gene O 6 -methylguanine DNA methyltransferase (MGMT) is transcriptionally silenced by promoter hypermeth...

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Principais autores: G. Toffoli, D. Rossi, G. Gaidano, E. Cecchin, M. Boiocchi, A. Carbone
פורמט: Artigo
שפה:Inglês
יצא לאור: SAGE Publishing 2003-07-01
סדרה:The International Journal of Biological Markers
גישה מקוונת:https://doi.org/10.1177/172460080301800310
תגים: הוספת תג
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