Protection against Malignant Progression of Spontaneously Developing Liver Tumors in Transgenic Mice Expressing O(6)‐Methylguanine‐DNA Methyltransferase

To study the effect of O(6)‐methylguanine‐DNA methyltransferase (MGMT) on carcinogenesis, we have previously generated MGMT transgenic mice overexpressing the bacterial MGMT gene, ada, and demonstrated that high MGMT levels in the liver suppress induction of liver tumors after treatment with an alky...

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書目詳細資料
發表在:Jpn J Cancer Res
Main Authors: Qin, Xiusheng, Zhang, Shaomin, Matsukuma, Shoichi, Zarkovic, Mirjana, Shimizu, Seiichiro, Ishikawa, Takatoshi, Nakatsuru, Yoko
格式: Artigo
語言:Inglês
出版: Blackwell Publishing Ltd 2000
主題:
Rapid Communication
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC5926285/
https://ncbi.nlm.nih.gov/pubmed/11092970
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1349-7006.2000.tb00888.x
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