Enhancement of the Anti‐tumor Effect of 5′‐Deoxy‐5‐fluorouridine by Transfection of Thymidine Phosphorylase Gene into Human Colon Cancer Cells

Thymidine phosphorylase (dThdPase) is an enzyme that converts 5′‐deoxy‐5‐fluorouridine (5′DFUR) to the toxic substance 5‐fluorouracil (5‐FU); it is also known to be a platelet‐derived endothelial cell growth factor. In order to investigate the feasibility of suicide gene therapy against colorectal c...

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Vydáno v:Jpn J Cancer Res
Hlavní autoři: Kanyama, Hiroki, Tomita, Naohiro, Yamano, Tomoki, Miyoshi, Yasuo, Ohue, Masayuki, Fujiwara, Yoshiyuki, Sekimoto, Mitsugu, Sakita, Isao, Tamaki, Yasuhiro, Monden, Morito
Médium: Artigo
Jazyk:Inglês
Vydáno: Blackwell Publishing Ltd 1999
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5926090/
https://ncbi.nlm.nih.gov/pubmed/10363585
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1349-7006.1999.tb00769.x
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