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Enhancement of the Anti‐tumor Effect of 5′‐Deoxy‐5‐fluorouridine by Transfection of Thymidine Phosphorylase Gene into Human Colon Cancer Cells

Thymidine phosphorylase (dThdPase) is an enzyme that converts 5′‐deoxy‐5‐fluorouridine (5′DFUR) to the toxic substance 5‐fluorouracil (5‐FU); it is also known to be a platelet‐derived endothelial cell growth factor. In order to investigate the feasibility of suicide gene therapy against colorectal c...

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Bibliografiske detaljer
Udgivet i:Jpn J Cancer Res
Main Authors: Kanyama, Hiroki, Tomita, Naohiro, Yamano, Tomoki, Miyoshi, Yasuo, Ohue, Masayuki, Fujiwara, Yoshiyuki, Sekimoto, Mitsugu, Sakita, Isao, Tamaki, Yasuhiro, Monden, Morito
Format: Artigo
Sprog:Inglês
Udgivet: Blackwell Publishing Ltd 1999
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5926090/
https://ncbi.nlm.nih.gov/pubmed/10363585
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1349-7006.1999.tb00769.x
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