Antiarrhythmic Effects of Carvedilol and Flecainide in Cardiomyocytes Derived from Catecholaminergic Polymorphic Ventricular Tachycardia Patients

Mutations in the cardiac ryanodine receptor (RYR2) are the leading cause for catecholaminergic polymorphic ventricular tachycardia (CPVT). In this study, we evaluated antiarrhythmic efficacy of carvedilol and flecainide in CPVT patient-specific induced pluripotent stem cell-derived cardiomyocytes (i...

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Detalles Bibliográficos
Publicado en:Stem Cells Int
Main Authors: Pölönen, R. P., Penttinen, K., Swan, H., Aalto-Setälä, K.
Formato: Artigo
Idioma:Inglês
Publicado: Hindawi 2018
Assuntos:
Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5924967/
https://ncbi.nlm.nih.gov/pubmed/29760739
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2018/9109503
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