Antiarrhythmic Effects of Carvedilol and Flecainide in Cardiomyocytes Derived from Catecholaminergic Polymorphic Ventricular Tachycardia Patients

Mutations in the cardiac ryanodine receptor (RYR2) are the leading cause for catecholaminergic polymorphic ventricular tachycardia (CPVT). In this study, we evaluated antiarrhythmic efficacy of carvedilol and flecainide in CPVT patient-specific induced pluripotent stem cell-derived cardiomyocytes (i...

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Dettagli Bibliografici
Pubblicato in:Stem Cells Int
Autori principali: Pölönen, R. P., Penttinen, K., Swan, H., Aalto-Setälä, K.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Hindawi 2018
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5924967/
https://ncbi.nlm.nih.gov/pubmed/29760739
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2018/9109503
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