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Necroptosis promotes cell-autonomous activation of proinflammatory cytokine gene expression

Necroptosis, a form of regulated necrotic cell death, is mediated by receptor interacting protein 1 (RIPK1), RIPK3, and mixed lineage kinase domain-like protein (MLKL). However, the mechanism by which necroptosis promotes inflammation is still unclear. Here we report that the expression of cytokines...

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Detalhes bibliográficos
Publicado no:Cell Death Dis
Main Authors: Zhu, Kezhou, Liang, Wei, Ma, Zaijun, Xu, Daichao, Cao, Shuangyi, Lu, Xiaojuan, Liu, Nan, Shan, Bing, Qian, Lihui, Yuan, Junying
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5923285/
https://ncbi.nlm.nih.gov/pubmed/29703889
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41419-018-0524-y
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