Pannexin‐1 limits the production of proinflammatory cytokines during necroptosis

The activation of mixed lineage kinase‐like (MLKL) by receptor‐interacting protein kinase‐3 (RIPK3) controls the execution of necroptosis, a regulated form of necrosis that occurs in apoptosis‐deficient conditions. Active oligomerized MLKL triggers the exposure of phosphatidylserine residues on the...

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Detalhes bibliográficos
Publicado no:EMBO Rep
Main Authors: Douanne, Tiphaine, André‐Grégoire, Gwennan, Trillet, Kilian, Thys, An, Papin, Antonin, Feyeux, Magalie, Hulin, Philippe, Chiron, David, Gavard, Julie, Bidère, Nicolas
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2019
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Reports
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6776911/
https://ncbi.nlm.nih.gov/pubmed/31410978
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embr.201947840
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