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The glycoprotein GP130 governs the surface presentation of the G protein–coupled receptor APLNR

Glioblastoma is one of the most lethal forms of adult cancer, with a median survival of ∼15 mo. Targeting glioblastoma stem-like cells (GSCs) at the origin of tumor formation and relapse may prove beneficial. In situ, GSCs are nested within the vascular bed in tight interaction with brain endothelia...

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Bibliographische Detailangaben
Veröffentlicht in:J Cell Biol
Hauptverfasser: Trillet, Kilian, Jacobs, Kathryn A., André-Grégoire, Gwennan, Thys, An, Maghe, Clément, Cruard, Jonathan, Minvielle, Stéphane, Diest, Sara Gonzalez, Montagnac, Guillaume, Bidère, Nicolas, Gavard, Julie
Format: Artigo
Sprache:Inglês
Veröffentlicht: Rockefeller University Press 2021
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8298102/
https://ncbi.nlm.nih.gov/pubmed/34287648
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.202004114
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