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Systemic stress signalling: understanding the cell non-autonomous control of proteostasis

Proteome maintenance is crucial to cellular health and viability, and is typically thought to be controlled in a cell-autonomous manner. However, recent evidence indicates that protein-folding defects can systemically activate proteostasis mechanisms through signalling pathways that coordinate stres...

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Detalles Bibliográficos
Publicado en:Nat Rev Mol Cell Biol
Autores principales: Taylor, Rebecca C., Berendzen, Kristen M., Dillin, Andrew
Formato: Artigo
Lenguaje:Inglês
Publicado: 2014
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5922984/
https://ncbi.nlm.nih.gov/pubmed/24556842
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nrm3752
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