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Systemic stress signalling: understanding the cell non-autonomous control of proteostasis
Proteome maintenance is crucial to cellular health and viability, and is typically thought to be controlled in a cell-autonomous manner. However, recent evidence indicates that protein-folding defects can systemically activate proteostasis mechanisms through signalling pathways that coordinate stres...
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| Publié dans: | Nat Rev Mol Cell Biol |
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| Auteurs principaux: | , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
2014
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5922984/ https://ncbi.nlm.nih.gov/pubmed/24556842 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nrm3752 |
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