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Epitope Blocking: Positive and Negative Effects on the Biodistribution of (125)I‐Labeled Anti‐Tac Disulfide‐stabilized Fv Fragment of Two Antibodies against Different Epitopes of the Circulating Antigen

Prior in vivo studies using the (125)I‐labeled anti‐Tac disulfide‐stabilized variable region fragment ((125)I‐anti‐Tac dsFv) of monoclonal antibody in the presence of the circulating soluble alpha subunit of the interleukin‐2 receptor (sIL‐2Rα) have shown formation of complexes which interfere with...

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Bibliografiske detaljer
Udgivet i:Jpn J Cancer Res
Main Authors: Kobayashi, Hisataka, Sun, Bao‐Fu, Han, Eui‐Sik, Kim, Meyoung‐Kon, Le, Nhat, Wang, Qing‐Cheng, Nelson, David L., Pastan, Ira, Waldmann, Thomas A., Paik, Chang H., Carrasquillo, Jorge A.
Format: Artigo
Sprog:Inglês
Udgivet: Blackwell Publishing Ltd 1998
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5921826/
https://ncbi.nlm.nih.gov/pubmed/9617350
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1349-7006.1998.tb00582.x
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