Epitope Blocking: Positive and Negative Effects on the Biodistribution of (125)I‐Labeled Anti‐Tac Disulfide‐stabilized Fv Fragment of Two Antibodies against Different Epitopes of the Circulating Antigen

Prior in vivo studies using the (125)I‐labeled anti‐Tac disulfide‐stabilized variable region fragment ((125)I‐anti‐Tac dsFv) of monoclonal antibody in the presence of the circulating soluble alpha subunit of the interleukin‐2 receptor (sIL‐2Rα) have shown formation of complexes which interfere with...

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Enregistré dans:
Détails bibliographiques
Publié dans:Jpn J Cancer Res
Auteurs principaux: Kobayashi, Hisataka, Sun, Bao‐Fu, Han, Eui‐Sik, Kim, Meyoung‐Kon, Le, Nhat, Wang, Qing‐Cheng, Nelson, David L., Pastan, Ira, Waldmann, Thomas A., Paik, Chang H., Carrasquillo, Jorge A.
Format: Artigo
Langue:Inglês
Publié: Blackwell Publishing Ltd 1998
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Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5921826/
https://ncbi.nlm.nih.gov/pubmed/9617350
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1349-7006.1998.tb00582.x
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