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Transduction of the Macrophage Colony‐stimulating Factor Gene into Human Multidrug Resistant Cancer Cells: Enhanced Therapeutic Efficacy of Monoclonal Anti‐P‐glycoprotein Antibody in Nude Mice

To develop a therapeutic modality for overcoming multidrug‐resistant (MDR) cancer with anti‐MDR1 antibody, we examined the effect of macrophage colony‐stimulating factor (M‐CSF) gene transfection into MDR AD10 cells on therapy of MDR cancer with anti‐MDR1 antihody (MRK17) in nude mice. MDR human ova...

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Publicat a:Jpn J Cancer Res
Autors principals: Sone, Saburo, Tsuruo, Takashi, Sato, Shigeo, Yano, Seiji, Nishioka, Yasuhiko, Shinohara, Tsutomu
Format: Artigo
Idioma:Inglês
Publicat: Blackwell Publishing Ltd 1996
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5921165/
https://ncbi.nlm.nih.gov/pubmed/8698627
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1349-7006.1996.tb00289.x
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