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Combination Therapy with Antibody and Interleukin–2 Gene Transfer against Multidrug–resistant Cancer Cells

In the present study, we examined the effect of intcrlcukin–2 (IL–2) gene transfer into multidrug resistance (MDR) cancer cells on the therapeutic efficacy of MRK16. Human MDR ovarian cancer cells, AD10, were transduced with a bicistronic IL–2 retrovirus, Ha–IL2–IRES–Neo. The G418resistant populatio...

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Dettagli Bibliografici
Pubblicato in:Jpn J Cancer Res
Autori principali: Shinohara, Tsutomu, Sugimoto, Yoshikazu, Sato, Shigeo, Sone, Saburo, Tsuruo, Takashi
Natura: Artigo
Lingua:Inglês
Pubblicazione: Blackwell Publishing Ltd 1997
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5921314/
https://ncbi.nlm.nih.gov/pubmed/9439686
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1349-7006.1997.tb00335.x
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