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Inhibition of Multidrug‐resistant Human Tumor Growth in Athymic Mice by Anti‐P‐glycoprotein Monoclonal Antibodies

In an effort to devise an effective treatment for human drug‐resistant cancers, we have developed monoclonal antibodies, MRK16 and 17, reactive to the multidrug transporter protein, P‐glycoprotein. The monoclonal antibodies given intravenously effectively prevented tumor development in athymic mice...

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Dades bibliogràfiques
Publicat a:Jpn J Cancer Res
Autors principals: Tsuruo, Takashi, Hamada, Hirofumi, Sato, Shigeo, Heike, Yuji
Format: Artigo
Idioma:Inglês
Publicat: Blackwell Publishing Ltd 1989
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5917818/
https://ncbi.nlm.nih.gov/pubmed/2571602
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1349-7006.1989.tb01688.x
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