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Inhibition of Multidrug‐resistant Human Tumor Growth in Athymic Mice by Anti‐P‐glycoprotein Monoclonal Antibodies

In an effort to devise an effective treatment for human drug‐resistant cancers, we have developed monoclonal antibodies, MRK16 and 17, reactive to the multidrug transporter protein, P‐glycoprotein. The monoclonal antibodies given intravenously effectively prevented tumor development in athymic mice...

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Detalhes bibliográficos
Publicado no:Jpn J Cancer Res
Main Authors: Tsuruo, Takashi, Hamada, Hirofumi, Sato, Shigeo, Heike, Yuji
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Publishing Ltd 1989
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5917818/
https://ncbi.nlm.nih.gov/pubmed/2571602
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1349-7006.1989.tb01688.x
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