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Inhibition of Multidrug‐resistant Human Tumor Growth in Athymic Mice by Anti‐P‐glycoprotein Monoclonal Antibodies

In an effort to devise an effective treatment for human drug‐resistant cancers, we have developed monoclonal antibodies, MRK16 and 17, reactive to the multidrug transporter protein, P‐glycoprotein. The monoclonal antibodies given intravenously effectively prevented tumor development in athymic mice...

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Detalles Bibliográficos
Publicado en:Jpn J Cancer Res
Autores principales: Tsuruo, Takashi, Hamada, Hirofumi, Sato, Shigeo, Heike, Yuji
Formato: Artigo
Lenguaje:Inglês
Publicado: Blackwell Publishing Ltd 1989
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5917818/
https://ncbi.nlm.nih.gov/pubmed/2571602
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1349-7006.1989.tb01688.x
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