Mouse‐Human Chimeric Antibody MH171 against the Multidrug Transporter P‐Glycoprotein

We have developed a mouse‐human chimeric antibody MH171, in which the antigen‐recognizing variable regions of the mouse monoclonal antibody MRK17 are joined with the constant regions of human IgG1 antibodies. The MRK17 recognizes specifically the multidrug transporter P‐glycoprotein and inhibits the...

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Udgivet i:Jpn J Cancer Res
Main Authors: Ariyoshi, Keiko, Hamada, Hirofumi, Naito, Mikihiko, Heike, Yuji, Seimiya, Hiroyuki, Maezawa, Kayoko, Tsuruo, Takashi
Format: Artigo
Sprog:Inglês
Udgivet: Blackwell Publishing Ltd 1992
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5918864/
https://ncbi.nlm.nih.gov/pubmed/1352281
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1349-7006.1992.tb01958.x
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