Mouse‐Human Chimeric Antibody MH171 against the Multidrug Transporter P‐Glycoprotein

We have developed a mouse‐human chimeric antibody MH171, in which the antigen‐recognizing variable regions of the mouse monoclonal antibody MRK17 are joined with the constant regions of human IgG1 antibodies. The MRK17 recognizes specifically the multidrug transporter P‐glycoprotein and inhibits the...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Jpn J Cancer Res
Prif Awduron: Ariyoshi, Keiko, Hamada, Hirofumi, Naito, Mikihiko, Heike, Yuji, Seimiya, Hiroyuki, Maezawa, Kayoko, Tsuruo, Takashi
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Blackwell Publishing Ltd 1992
Pynciau:
Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC5918864/
https://ncbi.nlm.nih.gov/pubmed/1352281
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1349-7006.1992.tb01958.x
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