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Enhancement of Reversing Effect of Cyclosporin A on Vincristine Resistance by Anti‐P‐glycoprotein Monoclonal Antibody MRK‐16

The synergistic effect of MRK‐16, a monoclonal antibody against P‐glycoprotein, and cyclosporin A (CsA) on the modulation of vincristine resistance was studied by isobologram analysis in three different, highly multidrug‐rcsistant tumor cells. In all cell lines, the synergistic effect was demonstrat...

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Detalhes bibliográficos
Publicado no:Jpn J Cancer Res
Main Authors: Naito, Mikihiko, Tsuge, Harumi, Kuroko, Chie, Tomida, Akihiro, Tsuruo, Takashi
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Publishing Ltd 1993
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5919166/
https://ncbi.nlm.nih.gov/pubmed/8100562
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1349-7006.1993.tb00164.x
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